• Increased Interleukin 18 Activity in Adolescents With Early-Onset Psychosis Is Associated With Cortisol and Depressive Symptoms 

      Wedervang-Resell, Kirsten; Friis, Svein; Lonning, Vera Louise Hiorth; Smelror, Runar; Johannessen, Cecilie Haggag; Reponen, Elina Johanna; Lyngstad, Siv Hege; Lekva, Tove; Aukrust, Pål; Ueland, Thor; Andreassen, Ole Andreas; Agartz, Ingrid; Myhre, Anne Margrethe (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-14)
      <i>Objective</i> - Evidence indicates that the pathophysiology of adult psychosis involves immune dysregulation, but its associations with stress are often not considered. The inflammatory cytokine interleukin (IL)-18, which is elevated in adult schizophrenia, is suggested to be sensitive to stress. We compared the associations of IL-18 with cortisol and clinical variables in adolescents with ...